Re: COVID-19 treatment and vaccine update thread
Posted: Fri May 14, 2021 7:21 pm
just a tiny volcano eruption by the largest active volcano in the world. I'll stay here and watch from afar

That is not dead which can eternal lie, and with strange aeons bring us some web forums whereupon we can gather
http://garbi.online/forum/
just a tiny volcano eruption by the largest active volcano in the world. I'll stay here and watch from afar
WalMart drops masks for vaccinated associates and customers (honor system, cause 'Murica) and offers all employees $75 to get the jab(s). (Not honor syst, cause 'Murica).YellowKing wrote: Fri May 14, 2021 9:34 am I think the fear is you've now opened the door for the lifting of mask mandates for businesses (since nobody is going to be enforcing vaccination cards, it's not happening). The vaccinated people will be fine, but now Target will be filled with a bunch of unmasked, unvaccinated people passing it around to each other, which opens the door for spread and mutation.
I'm assuming people smarter than me have crunched the numbers and calculated that the risk is low enough that it's worth letting the unvaccinated take a hit. They're counting on enough unvaccinated people to "do the right thing" and continue to wear a mask which puts a lot more faith in them than I have.
However, I'm also not a fan of dragging out restrictions forever on people who did do the right thing.
I wouldn't say it's immaterial. It's almost like there are multiple reasons that the "I'll take my chances, doesn't hurt anyone else" approach is wrong.El Guapo wrote: Fri May 14, 2021 5:08 pmThe financial cost of that hospital bed is immaterial for society, though. The spread across society is what matters.LawBeefaroni wrote: Fri May 14, 2021 4:51 pmIf that bed they're sleeping in is a hospital bed on a COVID ward, we all get to pay for the burden of their bad choices.stessier wrote: Fri May 14, 2021 8:41 am I don't understand the problem. If you are vaccinated, you will be fine and have a very, very low risk of spreading anything you might catch and not know about. Everyone else has made their bed and can sleep in it.
Could have been. It's too late now if there isn't data to feed into it (although it seems like a good bullet point when prepping for the next pandemic.)Smoove_B wrote: Fri May 14, 2021 7:12 pm So it's true - there isn't a United States level vaccination database, but there could be.
That's sad. In MA, fewer than 1% are skipping our second shots.Daehawk wrote: Fri May 14, 2021 6:00 pm They asked and reminded me so many times of my 2nd appointment date. They saw SO many cancels and missed ones I think they thought Id chicken out too.
They did.Ralph-Wiggum wrote: Sat May 15, 2021 10:01 am Didn’t the CDC guidelines specially point out that the new guidelines aren’t meant for healthcare facilities?
Was hoping I’d be in the clear, but this vaccine has hit me like a truck today. Got a fever and every part of my body - from my teeth to my toes - just aches horribly.Skinypupy wrote: Fri May 14, 2021 10:24 pm Got my second shot today.![]()
Sore arm and kinda achy in general, but the relief is palpable.
We don't routinely vaccinate those previously infected by the flu with the flu vaccine. But there's no doubt we are vaccinating plenty of people who were previously infected with the coronavirus, albeit perhaps unknowingly and completely asymptomatically. In which case they would predictably possess some degree of natural immune response and antibodies to fight the virus, hence the more intense side effects when they receive the coronavirus vaccine as compared to someone with no previous exposure to the virus:Daehawk wrote: Sat May 15, 2021 12:10 pm Its weird how this vaccine affects everyone in such extreme ways from nothing to super sick. Other than allergic reactions you dont hear that about the flu shots.
Dr. Mallika Marshall wrote:BOSTON (CBS) – There are certain side effects from the COVID-19 vaccine that may indicate a person was at one time infected with the coronavirus, according to a new study.
The study, which has not yet been peer-reviewed, surveyed almost 1,000 health care workers in the U.K. after they received their first Pfizer vaccine.
After vaccination, about four-percent of those previously infected with the coronavirus developed swollen lymph nodes compared to only one-percent of people without known previous infection.
Those previously infected were also more likely to report fever, muscle pain, and fatigue. Pain at the injection site and GI symptoms were about the same in both groups. And the interval between the time of infection and time of vaccination did not appear to be a factor.
But as a reminder, if you’ve had COVID-19 in the past, you still need to get vaccinated. And even though you may develop side effects, those side effects tend to be mild to moderate and last only 24-48 hours.
Yeah, it's been weird watching it develop. If anything, it's creating some uncertainty and distrust in the system. Not to mention anxiety for those who've had the AZ. As if it isn't enough that we're already far behind, now they got to add this to the mix as well. This whole saga has been like a rickety rollercoaster.FishPants wrote: Sat May 15, 2021 9:07 am Ontario is a continuing cluster fuck with Doug Ford not listening to medical professionals -- I won't be surprised if some day down the road we find out that the misinformation around astrazeneca wasn't sponsored by Pfizer; it's getting ridiculous. First the boomers won't take AZ, then GenXers get the call to use it before it's gone and we do in record time, now they are saying that there's risk of blood clots and maybe your second dose might be Pfizer instead.
You keep coming back to that, but the vast majority are reporting symptoms after the second shot, not the first. This suggests it's simply people reacting to the shot and nothing to do with previous infection.Anonymous Bosch wrote: Sat May 15, 2021 12:52 pmWe don't routinely vaccinate those previously infected by the flu with the flu vaccine. But there's no doubt we are vaccinating plenty of people who were previously infected with the coronavirus, albeit perhaps unknowingly and completely asymptomatically. In which case they would predictably possess some degree of natural immune response and antibodies to fight the virus, hence the more intense side effects when they receive the coronavirus vaccine as compared to someone with no previous exposure to the virus:Daehawk wrote: Sat May 15, 2021 12:10 pm Its weird how this vaccine affects everyone in such extreme ways from nothing to super sick. Other than allergic reactions you dont hear that about the flu shots.
Some COVID Vaccine Side Effects May Indicate You Were Once Infected, Study Suggests
Dr. Mallika Marshall wrote:BOSTON (CBS) – There are certain side effects from the COVID-19 vaccine that may indicate a person was at one time infected with the coronavirus, according to a new study.
The study, which has not yet been peer-reviewed, surveyed almost 1,000 health care workers in the U.K. after they received their first Pfizer vaccine.
After vaccination, about four-percent of those previously infected with the coronavirus developed swollen lymph nodes compared to only one-percent of people without known previous infection.
Those previously infected were also more likely to report fever, muscle pain, and fatigue. Pain at the injection site and GI symptoms were about the same in both groups. And the interval between the time of infection and time of vaccination did not appear to be a factor.
But as a reminder, if you’ve had COVID-19 in the past, you still need to get vaccinated. And even though you may develop side effects, those side effects tend to be mild to moderate and last only 24-48 hours.
I'm not suggesting it's the only factor, just that it is a factor.stessier wrote: Sat May 15, 2021 3:37 pmYou keep coming back to that, but the vast majority are reporting symptoms after the second shot, not the first. This suggests it's simply people reacting to the shot and nothing to do with previous infection.Anonymous Bosch wrote: Sat May 15, 2021 12:52 pmWe don't routinely vaccinate those previously infected by the flu with the flu vaccine. But there's no doubt we are vaccinating plenty of people who were previously infected with the coronavirus, albeit perhaps unknowingly and completely asymptomatically. In which case they would predictably possess some degree of natural immune response and antibodies to fight the virus, hence the more intense side effects when they receive the coronavirus vaccine as compared to someone with no previous exposure to the virus:Daehawk wrote: Sat May 15, 2021 12:10 pm Its weird how this vaccine affects everyone in such extreme ways from nothing to super sick. Other than allergic reactions you dont hear that about the flu shots.
Some COVID Vaccine Side Effects May Indicate You Were Once Infected, Study Suggests
Dr. Mallika Marshall wrote:BOSTON (CBS) – There are certain side effects from the COVID-19 vaccine that may indicate a person was at one time infected with the coronavirus, according to a new study.
The study, which has not yet been peer-reviewed, surveyed almost 1,000 health care workers in the U.K. after they received their first Pfizer vaccine.
After vaccination, about four-percent of those previously infected with the coronavirus developed swollen lymph nodes compared to only one-percent of people without known previous infection.
Those previously infected were also more likely to report fever, muscle pain, and fatigue. Pain at the injection site and GI symptoms were about the same in both groups. And the interval between the time of infection and time of vaccination did not appear to be a factor.
But as a reminder, if you’ve had COVID-19 in the past, you still need to get vaccinated. And even though you may develop side effects, those side effects tend to be mild to moderate and last only 24-48 hours.
Not years - Pfizer had already submitted for full approval. That could come by the end of the year as review usually takes about six months. This vaccine has proved to be remarkably safe and effective.Anonymous Bosch wrote: Sat May 15, 2021 3:51 pmI'm not suggesting it's the only factor, just that it is a factor.stessier wrote: Sat May 15, 2021 3:37 pmYou keep coming back to that, but the vast majority are reporting symptoms after the second shot, not the first. This suggests it's simply people reacting to the shot and nothing to do with previous infection.Anonymous Bosch wrote: Sat May 15, 2021 12:52 pmWe don't routinely vaccinate those previously infected by the flu with the flu vaccine. But there's no doubt we are vaccinating plenty of people who were previously infected with the coronavirus, albeit perhaps unknowingly and completely asymptomatically. In which case they would predictably possess some degree of natural immune response and antibodies to fight the virus, hence the more intense side effects when they receive the coronavirus vaccine as compared to someone with no previous exposure to the virus:Daehawk wrote: Sat May 15, 2021 12:10 pm Its weird how this vaccine affects everyone in such extreme ways from nothing to super sick. Other than allergic reactions you dont hear that about the flu shots.
Some COVID Vaccine Side Effects May Indicate You Were Once Infected, Study Suggests
Dr. Mallika Marshall wrote:BOSTON (CBS) – There are certain side effects from the COVID-19 vaccine that may indicate a person was at one time infected with the coronavirus, according to a new study.
The study, which has not yet been peer-reviewed, surveyed almost 1,000 health care workers in the U.K. after they received their first Pfizer vaccine.
After vaccination, about four-percent of those previously infected with the coronavirus developed swollen lymph nodes compared to only one-percent of people without known previous infection.
Those previously infected were also more likely to report fever, muscle pain, and fatigue. Pain at the injection site and GI symptoms were about the same in both groups. And the interval between the time of infection and time of vaccination did not appear to be a factor.
But as a reminder, if you’ve had COVID-19 in the past, you still need to get vaccinated. And even though you may develop side effects, those side effects tend to be mild to moderate and last only 24-48 hours.
The only reason we're fortunate enough to have the vaccine as soon as we did is because it received ‘Emergency Use’ authorization. 'Emergency Use’ authorized vaccines do not meet the criteria for a fully biologically licensed vaccine (that's why U.S. military service members still have the choice not to receive it), which takes years of efficacy and safety data. So there's plenty more to be learned, studied, and researched about the vaccine's side effects and their causes.
Quoting from the Johns Hopkins Coronavirus Resource Center:stessier wrote: Sat May 15, 2021 4:18 pm Not years - Pfizer had already submitted for full approval. That could come by the end of the year as review usually takes about six months.
coronavirus.jhu.edu wrote:TYPICAL TIMELINE
A typical vaccine development timeline takes 5 to 10 years, and sometimes longer, to assess whether the vaccine is safe and efficacious in clinical trials, complete the regulatory approval processes, and manufacture sufficient quantity of vaccine doses for widespread distribution.
Indeed, and I was not suggesting otherwise.stessier wrote: Sat May 15, 2021 4:18 pmThis vaccine has proved to be remarkably safe and effective.
That is not the only reason we're fortunate enough to have it as soon as we did.Anonymous Bosch wrote: Sat May 15, 2021 3:51 pm
The only reason we're fortunate enough to have the vaccine as soon as we did is because it received ‘Emergency Use’ authorization.
Sure, if you completely remove the context of my remark. But I was specifically referring to the authorization process rather than trying to suggest that BioNTech designing an mRNA vaccine by plugging the genetic code for the spike protein into its software had nothing whatsoever to do with the overall speed of its development. In case it was not obvious, I wasn't trying to provide a prolix paragraph detailing each and every contributary aspect that went into the vaccine's rapid development.Defiant wrote: Sat May 15, 2021 6:52 pmThat is not the only reason we're fortunate enough to have it as soon as we did.Anonymous Bosch wrote: Sat May 15, 2021 3:51 pm
The only reason we're fortunate enough to have the vaccine as soon as we did is because it received ‘Emergency Use’ authorization.
IIUC, some of the other reasons include MRNA technology (obviously only with regards to the MRNA vaccines), early work in the area, lots of funding to alleviate bottlenecks like manufacturing, etc. Oh yeah, and a worldwide pandemic might have led to more focus and raising it's priority.![]()
Fast track, priority review, and accelerated approval are all used by the FDA to speed up trials and approval. They can cut the typical timeline by half or more.Anonymous Bosch wrote: Sat May 15, 2021 7:27 pmSure, if you completely remove the context of my remark. But I was specifically referring to the authorization process rather than trying to suggest that BioNTech designing an mRNA vaccine by plugging the genetic code for the spike protein into its software had nothing whatsoever to do with the overall speed of its development. In case it was not obvious, I wasn't trying to provide a prolix paragraph detailing each and every contributary aspect that went into the vaccine's rapid development.Defiant wrote: Sat May 15, 2021 6:52 pmThat is not the only reason we're fortunate enough to have it as soon as we did.Anonymous Bosch wrote: Sat May 15, 2021 3:51 pm
The only reason we're fortunate enough to have the vaccine as soon as we did is because it received ‘Emergency Use’ authorization.
IIUC, some of the other reasons include MRNA technology (obviously only with regards to the MRNA vaccines), early work in the area, lots of funding to alleviate bottlenecks like manufacturing, etc. Oh yeah, and a worldwide pandemic might have led to more focus and raising it's priority.![]()
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Again, I was not trying to suggest otherwise. I only mentioned the EUA in the context of emphasizing the notion there's more to be learned, studied, and researched about the vaccine's side effects and their causes. Which will doubtless be further clarified as it goes through the process of becoming a fully biologically licensed vaccine, regardless of exactly how long that process takes.LawBeefaroni wrote: Sat May 15, 2021 8:26 pm Fast track, priority review, and accelerated approval are all used by the FDA to speed up trials and approval. They can cut the typical timeline by half or more.
EUA still bypassed all this but the FDA can approve in as little as 6 months under "normal" processes. What puts a lower limit on it are the trials. Good trials take several years at least.
Ontario is opening up eligibility for COVID-19 vaccines to everyone aged 18 and older a week ahead of schedule, the province said Monday, as public health units reported another 2,170 cases of the illness.
Those who meet the criteria can begin booking appointments through the province's online portal and call centre or through their local public health unit, depending on where they live, as of 8 a.m. ET Tuesday.
Ontario expects 2.2 million more doses of vaccines to arrive this week ahead of the Victoria Day long weekend. Among the additional doses is a shipment that was not supposed to land until next week, the province said in a news release.
Meanwhile, Ontarians who are 17 and set to turn 18 in 2021 will also be able to book an appointment for a shot of the Pfizer-BioNTech vaccine, the only one currently approved for use in adolescents aged 12 and older in Canada, starting Tuesday.
The province said it intends to start opening appointments through its online portal and call centre for those aged 12-17 the week of May 31. Officials say they are working with health units, school boards and First Nations, Inuit and Métis communities to finalize the details. Family members of adolescents who have not already been vaccinated will be encouraged to attend those same clinics for a shot, the province said.
Lastly, as of tomorrow, public health units administering the Pfizer vaccine through mobile and pop-up clinics, or via any clinics where walk-ins are permitted, will have the option to offer shots to those aged 12 and over.
- Manuscript highlights development of robust responses to both influenza and COVID-19 and protection against the SARS-CoV-2 virus
- Data shared via preprint server for biology, bioRxiv, ahead of publication
GAITHERSBURG, Md., May 10, 2021 /PRNewswire/ -- Novavax, Inc. (Nasdaq: NVAX), a biotechnology company developing next-generation vaccines for serious infectious diseases, today announced data from a preclinical study of the company's combination quadrivalent seasonal flu vaccine (NanoFlu™) and COVID-19 vaccine candidate (NVX-CoV2373). The NanoFlu/NVX-CoV2373 combination vaccine demonstrated positive immune responses to both influenza and SARS-CoV-2. A pre-print of the manuscript is available at bioRxiv.org.
The manuscript, titled 'Combination Respiratory Vaccine Containing Recombinant SARS-CoV-2 Spike and Quadrivalent Seasonal Influenza Hemagglutinin Nanoparticles with Matrix-M™ Adjuvant,' studied a combination vaccine comprising a quadrivalent nanoparticle influenza vaccine formulated together with a recombinant SARS-CoV-2 spike protein vaccine and Matrix-M™ adjuvant. The combination vaccine elicited robust responses to both influenza A and B and protected against the SARS-CoV-2 virus. Clinical studies of the combination vaccine are expected to begin by the end of the year.
The wife and I went to Disney Springs, the shopping and dining area at Walt Disney World, for an early lunch and to walk around and check it out since it's been at least three years since we've been there. A few days ago Disney dropped the requirement for masks to be worn outdoors, except in congested areas, like the security check points. Masks still have to be worn indoors unless actually seated in a restaurant. We at at the Rainforest Cafe, which was nice but expensive, and later got a churro; Disney churros are the bestEl Guapo wrote: Mon May 17, 2021 2:40 pm I took the subway on Saturday for the first time since March 2020. It was a little surreal being on the train again, but at the same time totally normal-ish. Mask compliance was pretty much at 100% (I did see one guy on the other side of the car with a mask on but below his nose). People were pretty spaced out for the most part (not super crowded).
Outdoors mask compliance is definitely down, not that I've been to anyplace outdoors with a large crowd lately. Downtown mask compliance varied between 30% - 70% depending on the time / group (significant variation). Overall probably slightly more people not wearing masks outside than wearing them.
The first one just preps the site. The second one delivers the transmitter, so yeah, a little bigger.Kasey Chang wrote: Mon May 17, 2021 2:37 pm Just got my second jab, and it did hurt a little more. The shot giver said they use a different needle for the 2nd shot (?!) didn't feel any different afterwards though. :-\
Morawska had spent more than two decades advising a different branch of the WHO on the impacts of air pollution. When it came to flecks of soot and ash belched out by smokestacks and tailpipes, the organization readily accepted the physics she was describing—that particles of many sizes can hang aloft, travel far, and be inhaled. Now, though, the WHO’s advisers seemed to be saying those same laws didn’t apply to virus-laced respiratory particles. To them, the word airborne only applied to particles smaller than 5 microns. Trapped in their group-specific jargon, the two camps on Zoom literally couldn’t understand one another.
I hope he's right, but if I'm going to trust anyone's guess it's his.Kids in the United States will likely be able to get COVID-19 vaccinations by the end of this year or the first quarter of 2022, Dr. Anthony Fauci, the nation’s top infectious disease expert, said at an event on Wednesday.
Fauci also noted the need for a COVID-19 booster shot within a year or so after getting the primary shot.
"I think we will almost certainly require a booster sometime within a year or so after getting the primary because the durability protection against coronavirus is generally not lifelong similar to measles," he said.