Octopus Overlords

FishPants wrote: Sat Jul 03, 2021 10:03 pm I read a story that vegas has nightlife returning when less than 50% have a single vaccine. That's crazy to think that many people just "cant be bothered".

Moderna has given out the first doses of an mRNA-based influenza vaccine to participants in an early-phase clinical trial, the company announced Wednesday.

Moderna ultimately plans to test the vaccine on about 180 people in the Phase 1/2 randomized, stratified, observer-blind trial. The trial will look at safety, different doses, and immune responses.

The vaccine, called mRNA-1010, is designed to target four lineages of influenza viruses that circulate seasonally each year, just like the current quadrivalent flu vaccines on the market. The four virus lineages are those identified by the World Health Organization as the ones to target for disease prevention each year—seasonal influenza type A lineages H1N1 and H3N2 as well as influenza type B lineages Yamagata and Victoria. If mRNA-1010 is shown to be effective against the yearly plague in later-stage trials, Moderna aims to eventually bundle it with three other mRNA-based vaccines to create a yearly one-stop shot.

In addition to influenza, this envisioned combination shot would target two other common respiratory viruses that circulate alongside influenza—respiratory syncytial virus (RSV) and human metapneumovirus (hMPV)—as well as the COVID-19 coronavirus, SARS-COV-2, which some experts have speculated could become seasonal. Currently, there are no licensed vaccines against either RSV or hMPV. And it's unclear if SARS-CoV-2 will become seasonal and/or if annual booster vaccines will be necessary.

YellowKing wrote: Wed Jul 07, 2021 4:39 pm I had to resist the urge to jump into a NextDoor thread where someone was complaining that the government encouraging people to get the vaccine was a "HIPPA" [sic] violation. And people were agreeing right and left.

The level of dumb I would have to stoop to in order to even begin that conversation was something I could not handle at 8:00 in the morning.

LawBeefaroni wrote: Thu Jul 08, 2021 9:15 am

YellowKing wrote: Wed Jul 07, 2021 4:39 pm I had to resist the urge to jump into a NextDoor thread where someone was complaining that the government encouraging people to get the vaccine was a "HIPPA" [sic] violation. And people were agreeing right and left.

The level of dumb I would have to stoop to in order to even begin that conversation was something I could not handle at 8:00 in the morning.

I too have to bite my tongue when I hear that kind of shit. HIPAA is so completely misunderstood and misused.

It lays the groundwork for EMR/PHR and protects PHI. That's it. It's not some kind of shield from public health.

Zaxxon wrote: Thu Jul 08, 2021 9:20 am

LawBeefaroni wrote: Thu Jul 08, 2021 9:15 am

YellowKing wrote: Wed Jul 07, 2021 4:39 pm I had to resist the urge to jump into a NextDoor thread where someone was complaining that the government encouraging people to get the vaccine was a "HIPPA" [sic] violation. And people were agreeing right and left.

The level of dumb I would have to stoop to in order to even begin that conversation was something I could not handle at 8:00 in the morning.

I too have to bite my tongue when I hear that kind of shit. HIPAA is so completely misunderstood and misused.

It lays the groundwork for EMR/PHR and protects PHI. That's it. It's not some kind of shield from public health.

But all HI is P, say the Karens.

NEW: Pfizer-BioNTech say they are pursuing booster vaccines because of Delta, and that boosters may be needed in 6-12 months.
But experts, CDC and FDA all say: Not so fast. There's no evidence that boosters will be needed -- maybe ever.

El Guapo wrote: Fri Jul 09, 2021 10:42 am Is that necessarily in conflict? Seems like it can both be true that there's not currently much evidence to support the necessity of boosters, and also that it makes sense for Pfizer and others to work on boosters in case such evidence develops later.

ImLawBoy wrote: Fri Jul 09, 2021 10:48 am

El Guapo wrote: Fri Jul 09, 2021 10:42 am Is that necessarily in conflict? Seems like it can both be true that there's not currently much evidence to support the necessity of boosters, and also that it makes sense for Pfizer and others to work on boosters in case such evidence develops later.

The conflict is that Pfizer is claiming they need approval on the boosters because they're seeing waning immunity. The FDA and CDC are disputing that.

There is a growing correlation between vaccinated Israelis who have been infected with the Delta variant of the coronavirus and those who were among the first to get the vaccine, possibly indicating that the vaccine’s protection fades over time, a report said Sunday.

However, some experts working with the Health Ministry cautioned that it was too early to draw conclusions, since the sample size was too small and those who were vaccinated first are mostly the elderly, who have a weaker immune system to begin with.

Daehawk wrote: Sun Jul 11, 2021 11:09 am I dont see the hubbub. If it fades get a booster if not then dont. People afraid of shots or something?

Blackhawk wrote: Sun Jul 11, 2021 11:40 am

Daehawk wrote: Sun Jul 11, 2021 11:09 am I dont see the hubbub. If it fades get a booster if not then dont. People afraid of shots or something?

People don't want to see drug companies manufacture a need and defraud humanity for billions in order to profit from a pandemic that has killed millions. If boosters are needed, absolutely. But we need to make sure they're actually needed rather than taking the fox's word on the hen house.

Especially if doing so makes the vaccine seem less appealing while we're still in the midst of convincing people to take it in the first place.

A 90-year-old Belgian woman who died from COVID-19 in March contracted both the UK and South African strain simultaneously, researchers said at a press conference on Sunday.

Her case, which was discussed at this year's European Congress on Clinical Microbiology & Infectious Diseases (ECCMID) as part of Belgian research, is believed to be the first of its kind.

Blackhawk wrote: Sun Jul 11, 2021 11:40 am

Daehawk wrote: Sun Jul 11, 2021 11:09 am I dont see the hubbub. If it fades get a booster if not then dont. People afraid of shots or something?

People don't want to see drug companies manufacture a need and defraud humanity for billions in order to profit from a pandemic that has killed millions. If boosters are needed, absolutely. But we need to make sure they're actually needed rather than taking the fox's word on the hen house.

Especially if doing so makes the vaccine seem less appealing while we're still in the midst of convincing people to take it in the first place.

Kraken wrote: Sat Jul 10, 2021 9:40 pm Wife found out this afternoon that she was exposed to covid last weekend, when she spent a day indoors with several fully-vaxxed friends. One of them whose general health is marginal came down with full-blown covid. Wife's getting tested tomorrow morning. She feels fine, but needs to know whether to quarantine or not. If she tests negative, that means she isn't carrying the virus, right? This is the first time either of us has knowingly been exposed so I'm not 100% clear on the protocol.

Jaymon wrote: Tue Jul 13, 2021 5:12 pm

Kraken wrote: Sat Jul 10, 2021 9:40 pm Wife found out this afternoon that she was exposed to covid last weekend, when she spent a day indoors with several fully-vaxxed friends. One of them whose general health is marginal came down with full-blown covid. Wife's getting tested tomorrow morning. She feels fine, but needs to know whether to quarantine or not. If she tests negative, that means she isn't carrying the virus, right? This is the first time either of us has knowingly been exposed so I'm not 100% clear on the protocol.

Covid can take up to a week before you test positive if you have been infected. Testing within 3 days of exposure is less effective. The best time for testing is 5-7 days after exposure. You should plan to quarantine for 14 days after a known exposure risk, to allow time for both testing and symptoms to appear.

El Guapo wrote: Tue Jul 13, 2021 5:27 pm

Jaymon wrote: Tue Jul 13, 2021 5:12 pm

Kraken wrote: Sat Jul 10, 2021 9:40 pm Wife found out this afternoon that she was exposed to covid last weekend, when she spent a day indoors with several fully-vaxxed friends. One of them whose general health is marginal came down with full-blown covid. Wife's getting tested tomorrow morning. She feels fine, but needs to know whether to quarantine or not. If she tests negative, that means she isn't carrying the virus, right? This is the first time either of us has knowingly been exposed so I'm not 100% clear on the protocol.

Covid can take up to a week before you test positive if you have been infected. Testing within 3 days of exposure is less effective. The best time for testing is 5-7 days after exposure. You should plan to quarantine for 14 days after a known exposure risk, to allow time for both testing and symptoms to appear.

Yeah, she should quarantine (and probably you too), at least until she gets her test results back.

The friend was fully vaccinated? Do you know about when the friend was vaccinated?

Immunity & immunodeficiency are complex & not an on /off state, rather a spectrum!
E.g., while it’s been shown that solid organ transplant receivers could benefit from 3rdSyringe, new data indicates 2SyringemRNA may be adequate for stem cell transplant patients.

"Individuals should not decide for themselves, public health agencies can, based on available data," she said in the tweet. "Data from mix and match studies of different vaccines are awaited - immunogenicity and safety both need to be evaluated."

Not knowing is really kind of the worst.

Kurth wrote: Wed Jul 14, 2021 12:53 pm I have yet to see a really good explanation. I think I’m immune compromised due to some medication I’m on for a chronic condition, but it’s not entirely clear.

Smoove_B wrote: Wed Jul 14, 2021 10:52 am I'm not exactly sure when that data or those studies will be published, but there really does seem to be lots of interest in getting solid information on what's best (which is nice to see, for a change).

Lorini wrote: Wed Jul 14, 2021 2:16 pm Well there has been a suggestion that workplaces should require that their workers either get vaccinated or get tested every day. Sounds like a plan to me.